Parkinson’s Disease and the THCV in cannabis.

New British and Spanish research on one of cannabis’ cannabinoids show its great potential for treating Parkinson’s disease. The cannabinoid is the lesser known but hugely interesting THCV, aka Delta-9-tetrahydrocannabivarin. The molecule is present to varying decrees in different strains of cannabis, from trace amounts to a hefty proportion.

Unlike your own body’s cannabinoid anandamide, or its phyto(plant based)-cannabinoid cousin, THC, THCV does not activate CB1 receptors in your endocannbinoid regulatory system. Activation of these CB1 receptors, found mainly on nerve cells, is responsible for most of THC’s psychoactive effects and medical benefits. THC also activates CB2 receptors, found more on immune cells and thought responsible for some of cannabis’ beneficial effects on some autoimmune disorders. Like THC, THCV also binds with and activates these CB2 receptors. Like THC, THCV is a powerful antioxidant, capable of sopping up cell-killing free radicals. Unlike THC, THCV does not activate CB1 receptors. Instead, it blocks (serves as an antagonist to) the activation of the CB1 system. It may play a major role in future treatments of cardiometabolic diseases and obesity.

The International Association of Cannabinoid Medicine reported the research as follows:

Parkinson’s disease
Spanish and British researchers investigated the effects of Delta-9-
tetrahydrocannabivarin (THCV) in an animal model of Parkinson’s
disease
. They concluded that “given its antioxidant properties and
its ability to activate CB2 but to block CB1 receptors, Delta-9-THCV
has a promising pharmacological profile for delaying disease
progression in PD and also for ameliorating parkinsonian symptoms.”
(Source: García C, et al. Br J Pharmacol. 2011 Feb 16. [in press]).

The fact that the research was British and Spanish, not American, is telling. Americans are not allowed to research cannabis and are denied access to marijuana for research. The pathetic paucity of medical cannabis research in the USA is a literal crime against humanity, a function of politics of prohibition. Americans by the millions suffer untreated pain, blinding glaucoma and immobilizing Parkinson’s disease while all research is denied, decade after decade. Instead of following a science-based assessment (which would demand a rush to research medical cannabis), American science has been held hostage to authoritarian bureaucrats.

7 thoughts on “Parkinson’s Disease and the THCV in cannabis.

  1. I rarely create comments, but i did a few searching and wound up here Parkinson’s Disease and the THCV in cannabis. » Your Brain On Bliss. And I actually do have a couple of questions for you if you tend not to mind. Could it be simply me or does it look like some of the remarks come across like left by brain dead folks? 😛 And, if you are writing on additional online sites, I would like to follow everything fresh you have to post. Would you make a list of all of your shared pages like your linkedin profile, Facebook page or twitter feed?

  2. I leave a comment whenever I appreciate a article on a site or I have something to add to the discussion. Usually it’s a result of the fire communicated in the article I looked at. And on this post Parkinson’s Disease and the THCV in cannabis. » Your Brain On Bliss. I was actually excited enough to write a leave a responsea response :-) I actually do have some questions for you if it’s allright. Is it simply me or do some of the responses appear like they are written by brain dead folks? 😛 And, if you are posting on additional places, I would like to follow you. Could you make a list every one of all your social sites like your linkedin profile, Facebook page or twitter feed?

  3. Fantastic items from you, man. I’ve be mindful your stuff prior to and you are simply extremely excellent. I actually like what you have acquired here, certainly like what you’re saying and the best way through which you say it. You’re making it enjoyable and you still take care of to stay it smart. I cant wait to read far more from you. This is actually a wonderful website.

  4. Properly it seems this internet site is somewhat sizzling, congratulations towards the owner! I try to go through as a lot as possible on the net once I’ve additional time. However it’s starting to get the norm for women and men to invest all day for the internet as a substitute of of mainly living, what a disgrace.

Leave a Reply

Your email address will not be published. Required fields are marked *