The Cannabinoid THCV May Treat Acne

Cannabis is a treasure trove of medicines. The plant’s 80+ cannabinoids offer treatment and relief from a long list of maladies: acne may now be included. The cannabinoid TCHV may offer a powerful treatment for acne, according to new European research.

Acne is an inflammation of the sebaceous glands, often on the faces of teenagers.    The gland’s duct can become blocked, perhaps from excess sebum produced by teenage hormones. Blocked glands can suffer bacterial infection, producing the common, if distressing, lesions on the skin.

Earlier, this same group found potential for the cannabinoid CBD (cannabidiol) in acne treatment.  Published in the Journal of Clinical Investigation, they concluded,

Collectively, our findings suggest that, due to the combined lipostatic, antiproliferative, and antiinflammatory effects, CBD has potential as a promising therapeutic agent for the treatment of acne vulgaris.”

The researchers followed up by studying five other cannabinoids as possible treatment of acne and related skin conditions. THCV, (-)-Δ9 -tetrahydrocannabivarin, CBC, CBDV, CBGV and CBD. They found different effects: CBG and CBGV may help in the treatment of dry skin. Concerning the opposite problem, excess lipogenesis and acne, the researchers found that:

CBC, CBDV and especially THCV show promise to become highly efficient, novel anti-acne agents. Moreover, based on their remarkable anti-inflammatory actions, phytocannabinoids could be efficient, yet safe novel tools in the management of cutaneous inflammations.